Peter Parker is an outcast high schooler abandoned by his parents as a boy, leaving him to be raised by his Uncle Ben and Aunt May. Like most teenagers, Peter is trying to figure out who he is and how he got to be the person he is today. As Peter discovers a mysterious briefcase that belonged to his father, he begins a quest to understand his parents' disappearance – leading him directly to Oscorp and the lab of Dr. Curt Connors, his father's former partner. As Spider-Man is set on a collision course with Connors' alter ego, The Lizard, Peter will make life-altering choices to use his powers and shape his destiny to become a hero.
Elenco: Andrew Garfield , Emma Stone , Rhys Ifans , Denis Leary , Campbell Scott , Irrfan Khan , Martin Sheen , Sally Field , Max Charles , Chris Zylka , Embeth Davidtz , Leif Gantvoort , Hannah Marks , Kelsey Asbille , C. Thomas Howell , Stan Lee , Michael Massee , Michael Papajohn , Kari Coleman , Charlie DePew , Skyler Gisondo , Jacob Rodier , Jake Keiffer , Kevin McCorkle , Barbara Eve Harris , Danielle Burgio , Michael Barra , Andy Pessoa , Andy Gladbach , Ring Hendricks-Tellefsen , Tom Waite , Keith Campbell , Steve DeCastro , James Chen , Alexander Bedria , John Burke , Jill Flint , Mark Daugherty , Milton González , Vincent Laresca , Damien Lemon , Ty Upshaw , Tia Texada , Jay Caputo , Terry Bozeman , Jennifer Lyons , Amber Stevens West , Zoey Deutch , Jody Cosgrove-Kao , Max Bogner , Ethan Cohn , Miles Elliot , Miranda LaDawn Hill , Amanda MacDonald , Maury Morgan , Amy Novondo .