Set during the Cold War, the Soviets – led by sword-wielding Irina Spalko – are in search of a crystal skull which has supernatural powers related to a mystical Lost City of Gold. After being captured and then escaping from them, Indy is coerced to head to Peru at the behest of a young man whose friend – and Indy's colleague – Professor Oxley has been captured for his knowledge of the skull's whereabouts.
Elenco: Harrison Ford , Cate Blanchett , Shia LaBeouf , Ray Winstone , Karen Allen , John Hurt , Jim Broadbent , Andrew Divoff , Igor Jijikine , Pavel Lychnikoff , Alan Dale , Ernie Reyes , Jr. , Dimitri Diatchenko , Ilia Volok , Emmanuel Todorov , Venya Manzyuk , Joel Stoffer , Neil Flynn , V.J. Foster , Chet Hanks , Brian Knutson , Dean Grimes , Sasha Spielberg , Nicole Luther , Sophia Stewart , Chris Todd , Dennis Nusbaum , T. Ryan Mooney , Audi Resendez , Helena Barrett , Carlos Linares , Gustavo Hernandez , Maria Luisa Minelli , Nito Larioza , Jon Valera , Kevin Collins , Robert Baker , Steven A. Miller .