Andrew returns to his hometown for the funeral of his mother, a journey that reconnects him with past friends. The trip coincides with his decision to stop taking his powerful antidepressants. A chance meeting with Sam - a girl also suffering from various maladies - opens up the possibility of rekindling emotional attachments, confronting his psychologist father, and perhaps beginning a new life.
Elenco: Zach Braff , Natalie Portman , Ian Holm , Peter Sarsgaard , Jean Smart , Armando Riesco , Jackie Hoffman , Method Man , Alex Burns , Ron Leibman , Jim Parsons , Michael Weston , Ann Dowd , Ato Essandoh , Denis O'Hare , Trisha LaFache , Geoffrey Arend , George C. Wolfe , Austin Lysy , Gary Gilbert , Jill Flint , Christopher Carley , Amy Ferguson , Wynter Kullman , Debbon Ayer , Yvette Mercedes , Jayne Houdyshell , Soara-Joye Ross , Joe Bacino , Seth Michael May , Kenneth Graymez , Ryan B. Moschetti , Tracey Antosiweicz , Ice , Magoo , Janine Strafaci , Kurt Siegelin .