After a car crash sends repressed cartoonist Stu Miley (Fraser) into a coma, he and the mischievous Monkeybone, his hilariously horny alter-ego, wake up in a wacked-out waystation for lost souls. When Monkeybone takes over Stu's body and escapes to wreak havoc on the real world, Stu has to find a way to stop him before his sister pulls the plug on reality forever!
Elenco: Brendan Fraser , Bridget Fonda , John Turturro , Chris Kattan , Giancarlo Esposito , Rose McGowan , Dave Foley , Megan Mullally , Bob Odenkirk , Whoopi Goldberg , Pat Kilbane , Lisa Zane , Sandra Thigpen , Wayne Wilderson , Amy Higgins , Alan Gelfant , Kristin Norton , Chris Hogan , Lucy Butler , John Sylvain , Lou Romano , Leon Laderach , Scott Rogers , Cris Thomas-Palomino , Tony Panterra , Ted Rooney , Christopher Franciosa , Mary Stein , Fred Pierce , Harper Roisman , Kristopher Logan , Scott Workman , Shawnee Free Jones , Ilia Volok , Edgar Allan Poe IV , Claudette Mink , Jon Bruno , Owen Masterson , Jen Sung , Tracy Zahoryin , Sunshine Deia Tutt , Jo Haugen Gash , Lindsay Bryan , Brooke Boisse , Meron Abebe , Mie Kringelbach , Rex Reddick , Sybil Azur , Anne Fletcher , Diane Mizota , Etty Lau , LaTonya Holmes , Lesli Jean Matta , Dawn Soler , Miko Watanbe , Frankie Pine , Anne King , Rachen Assapiomonwait , Veena Bidasha , Michael Anthony Jackson , Doug Jones , Arturo Gil , Jody St. Michael , Brian Steele , Leif Tilden , Tom Fisher , Joseph S. Griffo , Kim Timbers-Patteri , Lisa Ebeyer , Wayne Doba , Mark Viniello , Nathan Stein , Ed Holmes , Erica Gudis , Melinda Milton , Caroline A. Rice , Joe Ranft , Bruce Lanoil , Debi Durst , Phil Brotherton , Roger L. Jackson , Jym Dingler , Leslie Hedger , Toby Gleason , Allan Trautman , Mike Mitchell , Brendan Burns , Robert "Duckie" Carpenter , Thomas Haden Church , Jamie Donovan , Roger Ferreira , Wendy Fowler , Paul Guiles , Harry Jay Knowles , Jason Kravits , Skyler Marshall , George Meyers , Michelle Shaffer , Tom Tangen .