Gary Navarro is arrested for the second attempt to assassinate Dennis Ryland. Knowing she is the key to her mother's survival, Isabelle attempts to kill herself by jumping off the 4400 center building only to survive without a scratch. Matthew Ross expresses his displeasure at her actions and tells her of the destiny she is to face. Isabelle is troubled about what Matthew told her, but after a discussion with Shawn she decides it's her choice with what she does with her life. Matthew gives Isabelle a substance that can kill her if it's injected.
Elenco: Joel Gretsch , Chad Faust , Billy Campbell , Conchita Campbell , Samantha Ferris , Mahershala Ali , Megalyn Echikunwoke , Patrick John Flueger , Jacqueline McKenzie , Jenni Baird , Kaj-Erik Eriksen , Karina Lombard , Kavan Smith , Laura Allen , Mahershalalhashbaz Ali , Megalyn Echikunwoke , Natasha Gregson Wagner , Peter Coyote , Rhonda Dent , Samantha Ferris , Summer Glau , Tristin Leffler .