Eve, the Mother of All, unleashes a new monster upon the world: a black worm-slug that can enter the brain and force people to kill. Sam and Dean join forces with Bobby and Rufus and track it to a cannery, only to discover that Gwen and Samuel are also there looking for the monster... and none of them know who the monster is inside.
Elenco: Jensen Ackles , Jared Padalecki , Misha Collins , Alexander Calvert , Mark Pellegrino , Mark Sheppard , Alona Tal , Candice Accola , Felicia Day , Genevieve Padalecki , Jeffrey Dean Morgan , Julie McNiven , Katie Cassidy , Lauren Cohan , Osric Chau , Richard Speight Jr. , Rob Benedict , Samantha Ferris , Ty Olsson .