House is serving out a lengthy prison sentence for his various misdeeds, including his trip outside the country in an attempt to escape responsibility. Entirely cut off from his old life, House determines his current problems are the result of his inability to deal with people. Feeling he will never be able to practice medicine again, he plans instead to go back to university to earn a doctorate in physics - a field that will all but assure his isolation from other human beings.
Elenco: Hugh Laurie , Jesse Spencer , Omar Epps , Robert Sean Leonard , Peter Jacobson , Olivia Wilde , Odette Annable , Charlyne Yi , Anne Dudek , Kal Penn , Jennifer Crystal Foley , Bobbin Bergstrom , Sela Ward , Meaghan Martin , Michelle Trachtenberg , Odette Annable , Olivia Wilde , Peter Jacobson .