On the eve of Thanksgiving, House and the team take on the case of James Sidas, an exceptionally brilliant physicist and author who traded his successful career for a job as a courier. For the ailing patient, intelligence is a miserable burden that has prompted depression and addiction, and this, coupled with a myriad of strange symptoms, nearly stumps the team. Meanwhile the doctors at Princeton Plainsboro wrestle with strained personal relationships.
Elenco: Hugh Laurie , Jesse Spencer , Omar Epps , Robert Sean Leonard , Peter Jacobson , Olivia Wilde , Odette Annable , Charlyne Yi , Anne Dudek , Kal Penn , Jennifer Crystal Foley , Bobbin Bergstrom , Sela Ward , Meaghan Martin , Michelle Trachtenberg , Odette Annable , Olivia Wilde , Peter Jacobson .