Mark, with surprise guest Cynthia, returns to San Diego to be with his ailing mother. While trying to diagnose his mother's condition, Mark decides that he and Cynthia have no future together and tries to come to terms with his seemingly distant father.
Elenco: Maura Tierney , Parminder Nagra , Scott Grimes , Linda Cardellini , John Stamos , David Lyons , Angela Bassett , Laura Innes , Lily Mariye , Linda Cardellini , Maura Tierney , Mekhi Phifer , Noah Wyle , Parminder Nagra , Scott Grimes , Sherry Stringfield , Yvette Freeman , Eriq La Salle , Kellie Martin , John Stamos , Michael Michele , Erik Palladino , Angela Bassett , David Lyons , Chase Masterson , Swoosie Kurtz , Lisa Vidal , Laura Cerón .