In an attempt to talk to Sydney, Katya Derevko deliberately poisons herself and is temporally taken out from her cell. Once Nadia tells her sister about this, Sydney visits her aunt to tell her to stay away from Nadia. However, Katya unsettles Sydney by telling her that someone framed her mother as a means of getting her killed. Sydney sets off in search of the truth behind this story. Meanwhile, Vaughn becomes a rogue agent by getting involved with the people who might know his father's whereabouts. In the end, he and Sydney find out that the man behind these two plots is no other than A. Sloane. However, things are not exactly as they seem to be.
Elenco: Jennifer Garner , Ron Rifkin , Carl Lumbly , Kevin Weisman , Victor Garber , David Anders , Michael Vartan , Greg Grunberg , Merrin Dungey , Bradley Cooper , Rachel Nichols , Lena Olin , Melissa George , Amy Acker , Johnny Trí Nguyễn .